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LAC DPH Health Advisory: Increase in Extensively Drug-Resistant Shigella Cases in LAC

Key Messages

  • Extensively drug-resistant (XDR) Shigella cases are increasing in Los Angeles County (LAC).
  • XDR Shigella disproportionately affects men who have sex with men (MSM) and people living with HIV.
  • As Pride events begin this week, healthcare providers are asked to be vigilant for potential XDR Shigella infections and to test, treat, and report cases appropriately.
  • Due to rising antibiotic resistance, antibiotics should be reserved for patients with severe illness or underlying risk factors. Most Shigella infections are self-limiting.

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