The HALT Fentanyl Act recently passed has significant implications for researchers, especially those that are studying fentanyl-related substances (FRS). One of the major impacts from this Act is that it permanently classifies all fentanyl-related substances (FRS) as Schedule I substance under the Controlled Substance Act.
This means:
- These substances are considered to have no accepted medical use and a high potential for abuse
- Researchers must follow strict DEA registration and security protocols to work with them
Impacts on Research - Do you research fentanyl-related substances?
While the law is designed to fight the opioid crisis, it also affects how scientists can study these substances:
- Tighter Restrictions: Researchers must now follow strict federal rules to study any fentanyl-related compound, including special DEA registration and secure storage.
- Registration: Researchers must submit a completed application for registration (or modification of an existing DEA registration) within 90 days of a substance being scheduled under the Act.
If you no long need or studying fentanyl-related substances you should dispose of them as soon as possible by a
non-retriable method.
To Continue Working with Fentanyl-Related Substances:
Any individual or institution intending to conduct research on fentanyl-related substances that are now classified as Schedule I must apply.
The application must be submitted to the Drug Enforcement Administration (DEA) and include:
- A detailed research protocol.
- Security measures for handling Schedule I substances.
- Justification for the quantities requested.
- Institutional approvals (e.g., IRB, if applicable).
Once registered, researchers must comply with strict storage, recordkeeping, and reporting requirements. The DEA may inspect facilities to ensure compliance.
DEA - Schedule 1 Controlled Substance for Research Information
The Controlled Substance Program for Research provides resources for researchers to navigate Schedule 1 Registration process.
Schedule 1 Registration Resources
Questions email: controlledsubstances@ehs.ucla.edu